京都府立医科大学大学院医学研究科  免疫学(松田研究室)
Department of Immunology, Kyoto Prefectural University of Medicine

業績 - Publications -

【1】
Yamamoto K, Kishida T, Nakai K, Sato Y, Kotani S-I, Nishizawa Y, Yamamoto T, Kanamura N, & Mazda O.*
Direct phenotypic conversion of human fibroblasts into functional osteoblasts triggered by a blockade of the transforming growth factor-β signal
Scientific Reports (in press).
【2】
F. Boschetto, N. Toyama, S. Horiguchi, R. M. Bock, B. J. McEntire, T. Adachi, E. Marin, W. Zhu, O. Mazda, B. Sonny Bald, and G. Pezzotti*
In vitro antibacterial activity of oxide and non-oxide bioceramics for arthroplastic devices: II. Fourier transform infrared spectroscopy
Analyst. 2018 Apr 30;143(9):2128-2140. doi: 10.1039/c8an00234g.
PMID: 29666868
【3】
Pezzotti G, Marin E, Adachi T, Lerussi F, Rondinella A, Boschetto F, Zhu W, Kitajima T, Inada K, McEntire BJ, Bock RM, Bal BS, Mazda O.
Incorporating Si3N4 into PEEK to Produce Antibacterial, Osteocondutive, and Radiolucent Spinal Implants.
Macromol Biosci. 2018 Apr 24:e1800033. doi: 10.1002/mabi.201800033. [Epub ahead of print]
PMID: 29687593
【4】
Yamamoto H, Ueshima K, Saito M, Ikoma K, Ishida M, Goto T, Hayashi S, Ikegami A, Fujioka M, Mazda O, Kubo T.
Evaluation of femoral perfusion using dynamic contrast-enhanced MRI after simultaneous initiation of electrical stimulation and steroid treatment in an osteonecrosis model.
Electromagn Biol Med. 2018 Apr 30:1-11. doi: 10.1080/15368378.2018.1466310. [Epub ahead of print]
PMID: 29708772
【5】
Nakamura K, Kishida T, Ejima A, Tateyama R, Morishita S, Ono T, Murakoshi M, Sugiyama K, Nishino H, Mazda O.*
Bovine lactoferrin promotes energy expenditure via the cAMP-PKA signaling pathway in human reprogrammed brown adipocytes.
Biometals. 2018 May 9. doi: 10.1007/s10534-018-0103-9. [Epub ahead of print]
PMID: 29744695
【6】
Boschetto F, Adachi T, Horiguchi S, Fainozzi D, Parmigiani F, Marin E, Zhu W, McEntire B, Yamamoto T, Kanamura N, Mazda O, Ohgitani E, Pezzotti G.
Monitoring metabolic reactions in Staphylococcus epidermidis exposed to silicon nitride using in situ time-lapse Raman spectroscopy.
J Biomed Opt. 2018 May;23(5):1-10. doi: 10.1117/1.JBO.23.5.056002.
PMID: 29745132
【7】
Mori Y, Terauchi R, Shirai T, Tsuchida S, Mizoshiri N, Arai Y, Kishida T, Fujiwara H, Mazda O, Kubo T.
Suppression of heat shock protein 70 by siRNA enhances the antitumor effects of cisplatin in cultured human osteosarcoma cells.
Cell Stress Chaperones. 2017 Sep;22(5):699-706. doi: 10.1007/s12192-017-0793-x. Epub 2017 May 2. PMID: 28466152
【8】
G. Pezzotti*, R.M. Bock, T. Adachi, A. Rondinella, F. Boschetto, W. Zhu, E. Marin, B. McEntire, B. Sonny Bal, & O. Mazda
Silicon nitride surface chemistry: A potent regulator of mesenchymal progenitorcell activity in bone formation
Applied Materials Today 9: 82-95, 2017. https://doi.org/10.1016/j.apmt.2017.05.005
【9】
Mori Y, Shirai T, Terauchi R, Tsuchida S, Mizoshiri N, Hayashi D, Arai Y, Kishida T, Mazda O, & Kubo T
Antitumor effects of pristimerin on human osteosarcoma cells in vitro and in vivo
Onco Targets Ther. 28 November 2017 Volume 2017:10 Pages 5703—5710
【10】
Wakao J, Kishida T, Fumino S, Kimura K, Yamamoto K, Kotani S, Mizushima K, Naito Y, Yoshikawa T, Tajiri T, Mazda O.*
Efficient direct conversion of human fibroblasts into myogenic lineage induced by co-transduction with MYCL and MYOD1.
Biochem Biophys Res Commun. 2017 May 10. pii: S0006-291X(17)30921-X. doi: 10.1016/j.bbrc.2017.05.059. [Epub ahead of print]
PMID: 28501623
【11】
H. Tada, T. Kishida, H. Fujiwara, T. Kosuga, H. Konishi, S. Komatsu, A. Shiozaki, D. Ichikawa, K. Okamoto, E. Otsuji, & O. Mazda*
Reprogrammed chondrocytes engineered to produce interleukin-12 provide novel ex vivo immune-gene therapy for cancer
Immunotherapy. 2017 Mar;9(3):239-248. doi: 10.2217/imt-2016-0004.
PMID: 28231722
【12】
Sowa Y, Kishida T, Tomita K, Yamamoto K, Numajiri T, Mazda O.*
Direct Conversion of Human Fibroblasts into Schwann Cells that Facilitate Regeneration of Injured Peripheral Nerve In Vivo.
Stem Cells Transl Med. 2017 Apr;6(4):1207-1216. doi: 10.1002/sctm.16-0122. Epub 2017 Jan 9.
PMID: 28186702
【13】
Kimura K, Kishida T, Wakao J, Tanaka T, Higashi M, Fumino S, Aoi S, Furukawa T, Mazda O, Tajiri T.
Tumor-homing effect of human mesenchymal stem cells in a TH-MYCN mouse model of neuroblastoma.
J Pediatr Surg. 2016 Dec;51(12):2068-2073. doi: 10.1016/j.jpedsurg.2016.09.041.
PMID: 27686479
【14】
Ichimaru S, Nakagawa S, Arai Y*, Kishida T, Shin-Ya M, Honjo K, Tsuchida S, Inoue H, Fujiwara H, Shimomura S, Mazda O, Kubo T.
Hypoxia Potentiates Anabolic Effects of Exogenous Hyaluronic Acid in Rat Articular Cartilage.
Int J Mol Sci. 2016 Jun 25;17(7). pii: E1013. doi: 10.3390/ijms17071013.
PMID: 27347945
【15】
Kishida T, Ejima A, Mazda O*.
Specific Destruction of HIV Proviral p17 Gene in T Lymphoid Cells Achieved by the Genome Editing Technology.
Front Microbiol. 2016 Jun 28;7:1001. doi: 10.3389/fmicb.2016.01001. eCollection 2016.
PMID: 27446041
【16】
Yamamoto K., Sato Y., Honjo K., Ichioka H., Oseko F., Sowa Y., Yamamoto T., Kanamura N., Kishida T., Mazda O*
Generation of directly converted human osteoblasts that are free of exogenous gene and xenogenic protein
J Cell Biochem. 2016 Nov;117(11):2538-45. doi: 10.1002/jcb.25546. Epub 2016 Mar 31.
PMID: 26990860
【17】
Nishioka K, Kishida T, Masui S, Mazda O*
De novo CpG methylation on an artificial chromosome-like vector maintained for a long-term in mammalian cells.
Biotechnol Lett. 38 (4): 731-740, 2016.
【18】
Mizoshiri N, Kishida T, Yamamoto K, Shirai T, Terauchi R, Tsuchida S, Mori Y, Ejima A, Sato Y, Arai Y, Fujiwara H, Yamamoto T, Kanamura N, Mazda O*, Kubo T.
Transduction of Oct6 or Oct9 gene concomitant with Myc family gene induced osteoblast-like phenotypic conversion in normal human fibroblasts.
Biochem Biophys Res Commun. 467 (4): 1110-1116, 2015.
【19】
Yamamoto, K*. Yamamoto T, Honjo K, Ichioka H, Oseko F, Kishida T, Mazda O, & Kanamura N.
Electrical stimulation with periodic alternating intervals stimulates neuronal cells to produce neurotrophins and cytokines through activation of MAPK pathways.
Eur J Oral Sci. 123 (6): 403-408, 2015.
【20】
Kishida T, Ejima A, Yamamoto K, Tanaka S, Yamamoto T, Mazda O*.
Reprogrammed Functional Brown Adipocytes Ameliorate Insulin Resistance and Dyslipidemia in Diet-Induced Obesity and Type 2 Diabetes.
Stem Cell Reports. 5 (4): 569-581, 2015.
【21】
Sowa Y*. T. Kishida, T. Imura, T. Numajiri, K. Nishino, Y. Tabata, & O. Mazda
Adipose-derived stem cells promote peripheral nerve regeneration in vivo without differentiation into Schwann-like lineage.
Plast Reconstr Surg. 2016 Feb;137(2):318e-30e.
【22】
Ichioka H, Yamamoto T, Yamamoto K, Honjo KI, Adachi T, Oseko F, Mazda O, Kanamura N, & Kita M*
Biomechanical force induces the growth factor production in human periodontal ligament-derived cells.
Odontology. 2016 Jan;104(1):27-34.
【23】
Yamamoto K, Kishida T, Sato Y, Nishioka K, Ejima A, Fujiwara H, Kubo T, Yamamoto T, Kanamura N & Mazda O.*
Direct conversion of human fibroblasts into functional osteoblasts by defined factors.
Proc Natl Acad Sci USA. 2015 May 12;112(19):6152-7.
【24】
Ikegami A, Ueshima K, Saito M, Ikoma K, Fujioka M, Hayashi S, Ishida M, Fujiwara H, Mazda O, Kubo T.
Femoral perfusion after pulsed electromagnetic field stimulation in a steroid-induced osteonecrosis model.
Bioelectromagnetics. 2015 Jul;36(5):349-57.
【25】
Inoue H, Arai Y, Kishida T, Terauchi R, Honjo K, Nakagawa S, Tsuchida S, Matsuki T, Ueshima K, Fujiwara H, Mazda O, Kubo T.
Hydrostatic Pressure Influences HIF-2 Alpha Expression in Chondrocytes.
Int J Mol Sci. 2015 Jan 5;16(1):1043-50.
【26】
Fujioka K, Kishida T, Ejima A, Yamamoto K, Fujii W, Murakami K, Seno T, Yamamoto A, Kohno M, Oda R, Yamamoto T, Fujiwara H, Kawahito Y, & Mazda O*.
Inhibition of osteoclastogenesis by osteoblast-like cells genetically engineered to produce interleukin-10.
Biochem Biophys Res Commun. 2015 Jan 16;456(3):785-91.
【27】
Fujii H, Shin-Ya M, Takeda S, Hashimoto Y, Mukai S, Sawada S, Adachi T, Akiyoshi K*, Miki T, Mazda O*.
Cycloamylose-nanogel drug delivery system-mediated intratumor silencing of the vascular endothelial growth factor regulates neovascularization in tumor microenvironment
Cancer Sci. 105(12):1616-25, 2014.
【28】
Honjo K, Yamamoto T, Adachi T, Amemiya T, Kita M, Kanamura N, and Mazda O.
Evaluation of a dental pulp-derived cell sheet cultured on amniotic membrane substrate
Biomed Mater Eng. 25(2): 203-12, 2015.
【29】
Hayashi S, Fujioka M, Ikoma K, Saito M, Ueshima K, Ishida M, Kuribayashi M, Ikegami A, Mazda O, Kubo T.
Evaluation of femoral perfusion in a rabbit model of steroid-induced osteonecrosis by dynamic contrast-enhanced mri with a high magnetic field MRI system.
J Magn Reson Imaging. 41(4): 935-40, 2015.
【30】
Tsuchida S, Arai Y, Takahashi KA, Kishida T, Terauchi R, Honjo K, Nakagawa S, Inoue H, Ikoma K, Ueshima K, Matsuki T, Mazda O, Kubo T.
HIF-1α-induced HSP70 regulates anabolic responses in articular chondrocytes under hypoxic conditions.
J Orthop Res. 32(8):975-80, 2014.
【31】
Kami D, Kitani T, Kishida T, Mazda O, Toyoda M, Tomitaka A, Ota S, Ishii R, Takemura Y, Watanabe M, Umezawa A, Gojo S.
Pleiotropic functions of magnetic nanoparticles for ex vivo gene transfer. Nanomedicine. S1549-9634(14)00136-1, 2014.
【32】
Inoue H, Arai Y, Kishida T, Shin-Ya, M, Terauchi R, Nakagawa S, Saito M, Tsuchida, S, Inoue A, Shirai T, Fujiwara H, Mazda O, Kubo T.
Sonoporation-mediated transduction of siRNA ameliorated experimental arthritis using 3 MHz pulsed ultrasound.
Ultrasonics. 54(3):874-81, 2013.
【33】
Ohgitani E, Kita M, Mazda O, Imanishi J.
Combined administration of oseltamivir and hochu-ekki-to (TJ-41) dramatically decreases the viral load in lungs of senescence-accelerated mice during influenza virus infection.
Arch Virol. 159(2):267-75, 2013.
【34】
Kishida T, Cui FD, Ohgitani E, Gao F, Hayakawa K, Mazda O.
High Pressure Treatment under Subfreezing Temperature Results in Drastic Inactivation of Enveloped and Non-enveloped Viruses.
Biotechnol Lett. 35(8):1297-301.2013.
【35】
Nishigaki M, Yamamoto T, Ichioka H, Honjo KI, Yamamoto K, Oseko F, Kita M, Mazda O, Kanamura N.
β-cryptoxanthin regulates bone resorption related-cytokine production in human periodontal ligament cells.
Arch Oral Biol. 58(7):880-6, 2013.
【36】
Hiraoka N, Arai Y, Takahashi KA, Mazda O, Kishida T, Honjo K, Tsuchida S, Inoue H, Morino S, Suico MA, Kai H, Kubo T.
Mild electrical stimulation with heat stimulation increase heat shock protein 70 in articular chondrocyte.
J Orthop Res. 31(6):894-900, 2013.
【37】
Hagiwara K, Kishimoto S, Ishihara M, Koyama Y, Mazda O, Sato T.
*In vivo gene transfer using pDNA/chitosan/chondroitin sulfate ternary complexes: Influence of chondroitin sulfate on the stability of freeze-dried complexes and transgene expression in vivo.
J Gene Med.15(2):83-92, 2013.
【38】
Gao F, Kishida T, Ejima A, Gojo S & Mazda O*.
Myostatin acts as an autocrine/paracrine negative regulator in myoblast differentiation from human induced pluripotent stem cells.
Biochem. Biophys. Res. Commun 8; 431(2): 309-14, 2013.
【39】
Tsuchida S, Arai Y, Kishida T, Takahashi K, Honjo K, Terauchi R, Inoue H, Oda R, Mazda O, Kubo T.
Silencing the expression of connexin 43 decreases inflammation and joint destruction in experimental arthritis.
J. Orthop. Res. 31(4): 525-30, 2012.
【40】
Toriumi Y*, Kamei T, Murata K, Takahashi I, Suzuki N, Mazda O.
Utility of Maoto in an Influenza Season where Reduced Effectiveness of Oseltamivir was Observed - a Clinical.
Non-randomized Study in Children Forsch Komplementmed. 19(4): 179-86, 2012.
【41】
Nakagawa S, Arai Y*, Kishida T, Hiraoka N, Tsuchida S, Inoue H, Sakai R, Mazda O, Kubo T.
Lansoprazole Inhibits Nitric Oxide and Prostaglandin E(2) Production in Murine Macrophage RAW 264.7 Cells.
Inflammation.35(3): 1062-8, 2012
【42】
Fujita S, Arai Y*, Nakagawa S, Takahashi KA, Terauchi R, Inoue A, Tonomura H, Hiraoka N, Inoue H, Tsuchida S, Mazda O, Kubo T.
Combined microwave irradiation and intraarticular glutamine administration-induced HSP70 expression therapy prevents cartilage degradation in a rat osteoarthritis model.
J Orthop Res. 30(3): 401-7, 2011.
【43】
Yamamoto K*, Yamamoto T, Ichioka H, Akamatsu Y, Oseko F, Mazda O, Imanishi J, Kanamura N, Kita M.
Effects of mechanical stress on cytokine production in mandible-derived osteoblasts.
Oral Dis. 17(7): 712-9, 2011.
【44】
Yoshimoto K, Kishida T, Nakano Hi, Matsui M, Shin-Ya M, Shimada T, Nakai S, Imanishi J, Takeuchi M, Hisa Y, Mazda O.
Interleukin-28B acts synergistically with cisplatin to suppress the growth of head and neck squamous cell carcinoma.
J Immunother 34: 139-148, 2011
【45】
Hiraoka N, Takahashi KA, Arai Y, Sakao K, Mazda O, Kishida T, Honjo K, Tanaka S, Kubo T.
Intra-articular injection of hyaluronan restores the aberrant expression of matrix metalloproteinase-13 in osteoarthritic subchondral bone.
J Orthop Res 29: 354-360, 2010.
【46】
Shinoda M, Shin-Ya M, Naito Y, Kishida T, Ito R, Suzuki N, Yasuda H, Sakagami J, Imanishi J, Kataoka K, Mazda O, Yoshikawa T.
Early-stage blocking of Notch signaling inhibits the depletion of goblet cells in dextran sodium sulfate-induced colitis in mice.
J Gastroenterol. 45: 608-617, 2010.
【47】
Nakai N, Kishida T, Hartmann G, Katoh N, Imanishi J, Kishimoto S, Mazda O.
Mitf silencing cooperates with IL-12 gene transfer to inhibit melanoma in mice.
Int Immunopharmacol 10: 540-545, 2010.
【48】
Honjo K, Takahashi KA, Mazda O, Kishida T, Shin-Ya M, Tokunaga D, Arai Y, Inoue A, Hiraoka N, Imanishi J, Kubo T.
MDR1a/1b gene silencing enhances drug sensitivity in rat fibroblast-like synoviocytes.
J Gene Med 12: 219-227, 2010.
【49】
Nakagawa S, Arai Y, Mazda O, Kishida T, Takahashi KA, Sakao K, Saito M, Honjo K, Imanishi J, Kubo T.
N-acetylcysteine prevents nitric oxide-induced chondrocyte apoptosis and cartilage degeneration in an experimental model of osteoarthritis.
J Orthop Res 28: 156-163, 2010.
【50】
Sakao K, Takahashi KA, Arai Y, Saito M, Honjo K, Hiraoka N, Kishida T, Mazda O, Imanishi J, Kubo T.
Asporin and transforming growth factor-β gene expression in osteoblasts from subchondral bone and osteophytes in osteoarthritis.
J Orthop Sci 14: 738-747, 2009.
【51】
Hasegawa U, Sawada SI, Shimizu T, Kishida T, Otsuji E, Mazda O, Akiyoshi K.
Raspberry-like assembly of cross-linked nanogels for protein delivery.
J Control Release 140: 312-317, 2009.
【52】
Hashimoto T, Tachibana Y, Nozaki H, Mazda O, Niidome T, Murakami A, Yamaoka T.
Intracellular enzyme-responsive fragmentation of nonviral gene carriers leads to polyplex destabilization and enhanced transgene expression.
Chem Lett 38: 718-719. 2009.
【53】
Matsui M, Kishida T, Nakano H, Yoshimoto K, Shin-Ya M, Shimada T, Nakai S, Imanishi J, Yoshimoto T, Hisa Y, Mazda O.
Interleukin-27 activates natural killer cells and suppresses NK-resistant head and neck squamous cell carcinoma through inducing antibody-dependent cellular cytotoxicity.
Cancer Res 69: 2523-2530, 2009.
【54】
Sakao K, Takahashi KA, Arai Y, Saito M, Honjo K, Hiraoka N, Asada H, Shin-Ya M, Imanishi J, Mazda O, Kubo T.
Osteoblasts derived from osteophytes produce inteleukin-6, interleukin-8 and matrix metalloproteinase-13 in osteoarthritis.
J Bone Miner Metab 27: 412-423, 2009.
【55】
Inoue A, Takahashi KA, Mazda O, Arai Y, Saito M, Kishida T, Shin-Ya M, Morihara T, Tonomura H, Sakao K, Imanishi J, Kubo T.
Comparison of anti-rheumatic effects of local RNAi-based Therapy in collagen induced arthritis rats using various cytokine genes as molecular targets.
Mod Rheumatol 19: 125-133, 2009.
【56】
Nakai N, Katoh N, Germeraad WTV, Kishida T, Ueda E, Takenaka H, Mazda O, Kishimoto S.
Immunohistological analysis of peptide-induced delayed-type hypersensitivity in advanced melanoma patients treated with melanoma antigen-pulsed mature monocyte-derived dendritic cell vaccination.
J Dermatol Sci 53: 40-47, 2009.
【57】
Ito R, Kita M, Shin-Ya M, Kishida T, Urano A, Takada R, Sakagami J, Imanishi J, Iwakura Y, Okanoue T, Yoshikawa T, Kataoka K, Mazda O.
Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice.
Biochem Biophys Res Commun 377: 12-16, 2008.
【58】
Sakao K, Takahashi KA, Arai Y, Inoue A, Tonomura H, Saito M, Yamamoto T, Kanamura N, Imanishi J, Mazda O, Kubo T.
Induction of chondrogenic phenotype in synovium-derived progenitor cells by intermittent hydrostatic pressure.
Osteoarthr Cartilage 16: 805-814, 2008.
【59】
Sakao K, Takahashi KA, Mazda O, Arai Y, Tonomura H, Inoue A, Saito M, Fujioka M, Takamiya H, Imanishi J, Kubo T.
Enhanced expression of interleukin-6, matrix metalloproteinase-13, and receptor activator of NF-kappaB ligand in cells derived from osteoarthritic subchondral bone.
J Orthop Sci 13: 202-210, 2008.
【60】
Shimizu T, Kishida T, Hasegawa U, Ueda Y, Imanishi J, Yamagishi H, Akiyoshi K, Otsuji E, Mazda O.
Nanogel DDS enables sustained release of IL-12 for tumor immunotherapy.
Biochem Biophys Res Commun 367: 330-335, 2008.
【61】
Kishida T, Asada H, Kubo K, Sato Y, Shin-Ya M, Imanishi J, Yoshikawa K, Mazda O.
Pleiotrophic functions of Epstein-Barr virus nuclear antigen-1 (EBNA-1) and oriP differentially contribute to the efficacy of transfection/expression of exogenous gene in mammalian cells.
J Biotechnol 133: 201-207, 2008.
【62】
Tonomura H, Takahashi KA, Mazda O, Arai Y, Shin-Ya M, Inoue A, Honjo K, Hojo T, Imanishi J, Kubo T.
Effects of heat stimulation via microwave applicator on cartilage matrix gene and HSP70 expression in the rabbit knee joint.
J Orthop Res 26: 34-41, 2008.
【63】
Kishida T, Hiromura Y, Shin-Ya M, Asada H, Kuriyama H, Sugai M, Shimizu A, Yokota Y, Hama T, Imanishi J, Hisa Y, Mazda O.
IL-21 induces inhibitor of differentiation 2 (Id2) and leads to complete abrogation of anaphylaxis in mice.
J Immunol 179: 8554-8561, 2007.
【64】
Hiromura Y, Kishida T, Nakano H, Hama T, Imanishi J, Hisa Y, Mazda O.
IL-21 administration into the nostril alleviates murine allergic rhinitis.
J Immunol 179: 7157-7165, 2007.
【65】
Saito M, Mazda O, Takahashi KA, Arai Y, Kishida T, Shin-Ya M, Inoue A, Tonomura H, Sakao K, Morihara T, Imanishi J, Kawata M, Kubo T.
Sonoporation-mediated transduction of pDNA/siRNA into joint synovium in vivo.
J Orthop Res 25: 1308-1316, 2007.
【66】
Nakai N, Kishida T, Shin-Ya M, Imanishi J, Ueda Y, Kishimoto S, Mazda O.
Therapeutic RNA interference of malignant melanoma by electrotransfer of small interfering RNA targeting Mitf.
Gene Ther 14: 357-365, 2007.
【67】
Ishii M, Iwai M, Harada Y, Kishida T, Asada H, Shin-Ya M, Itoh Y, Imanishi J, Okanoue T, Mazda O.
Soluble TRAIL gene and actinomycin D synergistically suppressed multiple metastasis of TRAIL-resistant colon cancer in the liver.
Cancer Letters 245: 134-143, 2007.
【68】
Ito R, Shin-Ya M, Kishida T, Urano A, Takada R, Sakagami J, Imanishi J, Kita M, Ueda Y, Iwakura Y, Kataoka K, Okanoue T, Mazda O.
Interferon-gamma is Causatively involved in experimental inflammatory bowel disease in mice.
Exp Clin Immunol 146: 330-338, 2006.
【69】
Iida Y, Oda Y, Nakamori S, Tsunoda S, Kishida T, Gojo S, Shin-Ya M, Asada H, Imanishi J, Yoshikawa T, Matsubara H, Mazda O.
Transthoracic direct current (DC) shock facilitates intramyocardial transfection of naked plasmid DNA infused via coronary vessels in canines.
Gene Ther 13: 906-916, 2006.
【70】
Tonomura H, Takahashi KA, Mazda O, Arai Y, Inoue A, Terauchi R, Shin-Ya M, Kishida T, Imanishi J, Kubo T.
Glutamine protects articular chondrocytes from heat stress and NO-induced apoptosis with HSP70 expression.
Osteoarthr Cartilage 14: 545-553, 2006.
【71】
Asada H, Kishida T, Hirai H, Shin-Ya M, Imanishi J, Takeuchi M, Mazda O.
Combination vaccine of dendritic Cells (DCs) and T cells effectively suppressed preestablished malignant melanoma in mice.
Cancer Letters 240: 83-93, 2006.
【72】
Nakano H, Kishida T, Asada H, Shin-Ya M, Shinomiya T, Imanishi J, Shimada T, Nakai S, Takeuchi M, Hisa Y and Mazda O.
Interleukin-21 triggers both cellular and humoral immune responses leading to therapeutic antitumor effects against head and neck squamous cell carcinoma.
J Gene Med 8: 90-99, 2006.