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 HOME> 研究業績

 2005

論文


Tanaka H, Hamamoto T, Takamatsu T
Toward an Integrated Understanding of the Purkinje Fibers in the Heart: The Functional and Morphological Interconnection between the Purkinje Fibers and Ventricular Muscle.
Acta Histochem.Cytochem.38(4):257-265, 2005.


Hamamoto T, Tanaka H, Mani H, Tanabe T, Fujiwara K,
Nakagami T, Horie M, Oyamada M, Takamatsu T.
In situ Ca2+ dynamics of Purkinje fibers and its interconnection with subjacentventricular myocytes.
J Mol Cell Cardiol. 2005 38:561-9.


Ota T, Fukuyama H, Ishihara Y, Tanaka H, Takamatsu T.
In situ fluorescence imaging of organs through compact scanning head for confocal laser microscopy.
J Biomed Opt. 2005 10:24010.


Tanabe T, Oyamada M, Fujita K, Dai P, Tanaka H,
Takamatsu T.
Multiphoton excitation-evoked chromophore-assisted laser inactivation using green fluorescent protein.
Nat Methods. 2005 Jul;2(7):503-5.


Shiba D, Takamatsu T, Yokoyama T.
Primary cilia of inv/inv mouse renal epithelial cells sense physiological fluid flow: bending of primary cilia and
Ca2+ influx.

Cell Struct Funct. 2005;30(2):93-100.


Oyamada M, Oyamada Y, Takamatsu T.
Regulation of connexin expression.
Biochim Biophys Acta. 2005 Dec 20;1719(1-2):6-23. Epub 2005 Nov 18. Review.


著書


高松哲郎
序論: 蛍光を用いたバイオイメ−ジングの基礎
−生体レベルでの機能分子解析に向けて−

バイオイメ−ジングがわかる
−細胞内分子を観察する多様な技術とその原理−,
高松哲郎編, pp. 10−19, 羊土社, 東京, 2005. 9


田邉卓爾, 高松哲郎
多光子CALI法によるタンパク質機能阻害法.
高松哲郎編. バイオイメ−ジングがわかる
東京: 羊土社, 104−108, 2005


原田義規, 高松哲郎
レ−ザ−顕微鏡の基本.
日本組織細胞化学会編. 組織細胞化学2005
京都: 中西印刷, 51−57, 2005


総説


田中秀央, 高松哲郎
心筋細胞のカルシウムハンドリングと不整脈
カレントテラピ− 23: 231−235, 2005


小山田正人, 小西英一, 小山田ゆみ子
ギャップ結合と病態発生.  
細胞 37: 29−33, 2005


学会発表


Tanabe, T and Takamatsu, T
Multiphoton excitation−evoked chromophore−assisted laser inactivation using green fluorescent protein.
Focus on Microscopy 2005,
March 21, 2005, Jena


Tetsuro Takamatsu
In Situ Visualization and Manipulation of Functional Molecules
by Nonlinear Optical Microscopy

International Society of Cancer Prevention Symposium
May 21, 2005, Kyoto


高松哲郎
生命機構を可視化する新しい光学顕微鏡技術
日本病理学会技術講習会
2005年4月15日 パシフィコ横浜


高松哲郎
レ−ザ顕微鏡を使いこなすための基本(II)
光学顕微鏡の基礎と応用

第31回レ−ザ顕微鏡研究会ワ−クショップ
2005年6月29日 埼玉


高松哲郎
レ−ザ顕微鏡の基本
第30回組織細胞化学講習会
2005年8月3日 大阪


高松哲郎
光による細胞機能の可視化
バイオイメ−ジング学会ライブセルイメ−ジング講習会
2005年10月11日 つくば


高松哲郎
非線形光学顕微鏡を用いたバイオイメ−ジング
日本オプトメカトロニクス協会
第3回フォトンテクノロジ−技術部会招待講演
2005年11月29日 東京


高松哲郎
光による細胞の刺激と加工−生体への応用を目指して−
再生医療学会ワ−クショップ「バイオイメ−ジング」
2005年3月1−2日 大阪


高松哲郎
2光子を用いた細胞機能分子の解析
日本顕微鏡学会ニュ−マイクロスコ−プ分科会シンポジウム 
2005年3月10日 東京


高松哲郎
二光子吸収による細胞機能の制御
日本顕微鏡学会第61回学術講演会シンポジウム 
2005年4月15日 つくば


高松哲郎
近赤外超短パルスレ−ザ−を用いた細胞機能分子の解析
第31回レ−ザ顕微鏡研究会シンポジウム
「ナノバイオイメ−ジングの世界」 −中村 収先生の業績とともに−.
2005年7月1日 埼玉


高松哲郎
非線形光学顕微鏡による生命機能の解明
第26回日本レ−ザ−医学会シンポジウム
「レ−ザ−光の未知の可能性」
2005年9月9日 東京


高松哲郎
中村先生との出会い: 三次元顕微鏡
日本分光学会 顕微分光部会中村先生追悼シンポジウム
2005年9月28日 大阪


田邉卓爾, 小山田正人, 藤田克昌, 戴平, 田中秀央, 高松哲郎
2光子吸収CALIを用いた機能分子の制御
日本組織細胞化学会第46回総会・学術集会, 京都,
2005年10月2日(シンポジウム)


小山田正人, 鈴木敏弘, 高松哲郎
ギャップ結合の異常と疾患
日本組織細胞化学会第46回総会・学術集会, 京都,
2005年10月1日(ワ−クショップ)


Tanaka H, Tsujii E, Mani H, Takamatsu T
Arrhythmogenic intracellular calcium dynamics in the injured heart viewed by in situ real−time confocal microscopy
第28回心筋代謝研究会
2005年7月26日, 浜松


Mani H, Tanaka H, Tanabe T, Nakagami T, Fujiwara K, Dai P, Oyamada M, Takamatsu T
Irrevresible myocardial injury by Ca2+ paradox induces contraction band necrosis in the working heart by influx through the Na2+−Ca2+ exchange
Scientific Sessions 2005 American Heart Association,
Nov 25, 2005, Dallas, TX, USA.


Harada Y, Ota T, Dai P, Tanaka H, Oyamada M, Kawata S, Takamatsu T
Young's modulus of primary cilia measured with optical tweezers
The American Society for Cell Biology 45th Annual Meeting.
Dec 10−14, 2005, San Francisco, CA, USA


Tanabe T, Oyamada M, Fujita K, Dai P, Tanaka H, Takamatsu T
Multiphoton Excitation−evoked Chromophore−assisted Laser Inactivation Using Green Fluorescent Protein
The American Society for Cell Biology 45th Annual Meeting.
Dec 10−14, 2005, San Francisco, CA, USA


Tanaka H, Hamamoto T, Takamatsu T
In situ confocal visualization of intracellular calcium dynamics at the Purkinje−ventricular interconnection of the Langendorff−perfused rat heart
Cardiac Arrhythmia Mechanism. Gordon Research Conference.
Feb 20−25, 2005, Buelton CA, USA


Oyamada M, Zhou W, Oyamada Y, Takamatsu T
Changes in connexin43 localization during ultraviolet light−induced apoptosis in HeLa cells expressing Cx43−EGFP: Comparison with mitochondrial membrane potential
Gap Junction Conference 2005, Whistler,
August 13−18, 2005


Oyamada Y, Takamatsu T, Oyamada M
Formation of tubular structures containing gap−junction plaques during cell dissociation by trypsinization revealed by time−lapse imaging of cells expressing connexin−GFP
Gap Junction Conference 2005, Whistler,
August 13−18, 2005


Suzuki T, Matsunami T, Hisa Y, Takata K, Takamatsu T, Oyamada M
Gap junctions between GLUT1−positive and −negative cells in the cochlea: Their possible roles in intercellular transport of glucose over the blood−inner ear barrier
Gap Junction Conference 2005, Whistler,
August 13−18, 2005


 2004

論文


Hirakawa H, Okajima S, Nagaoka T, Kubo T, Takamatsu T, Oyamada M.
Regional differences in blood-nerve barrier function and tight-junction protein expression within the rat dorsal root ganglion.
NeuroReport 2004; 15:405-8.


著書


Oyamada M, Oyamada Y, Takamatsu T.
Regulation of gap junction protein genes in differentiating ES cells. In Lanza R, Gearhart J, Hogan B, Melton D, Pedersen R, Thomson J, West Meds. Handbook of Stem Cells.
San Diego, Academic Press, 101−109 (2004).


田邊卓爾, 高松哲郎
マルチフォトンレ−ザ−顕微鏡 
高田邦昭編, 初めてでもできる共焦点顕微鏡活用プロトコ−ル,
羊土社, 東京, 187−191


万井弘基, 田中秀央, 高松哲郎
ニポウ板を使った共焦点顕微鏡.  
田邦昭編, 初めてでもできる共焦点顕微鏡活用プロトコ−ル,
羊土社, 東京, 196−200, 2004. 1. 1


中上拓男, 辻井英治, 浜本徹, 田中秀央
第4項 心筋虚血. モデルの動物の作成と維持
東京: 株式会社エル・アイ・シ−, 246−251, 2004


総説


高松哲郎
さまざまな展開をみせる最近の顕微鏡技術巻頭言「究極の顕微鏡」 
光学33,  693, 2004


田中秀央, 山元康敏, 高松哲郎
蛍光抗体法と共焦点レ−ザ−顕微鏡. 特集 病理診断における分子生物学 第3部 分子生物学の実践 B. in situ 検出法
病理と臨床 22: 338−343, 2004


田中秀央, 高松哲郎
特集 心筋研究の最前線 心筋細胞内のカルシウム波
生体の科学 55(4): 278−284, 2004


小山田ゆみ子, 小山田正人
心筋症の遺伝子異常と病態発生. 特集 病理診断における分子生物学 第2部 診断への応用と展望 B. 変性疾患
病理と臨床 22: 247−254, 2004


学会発表


Tetsuro Takamatsu
In situ Ca2+ imaging of the heart
Symposium "Three−dimensional structure of biological

materials" in 8th Asia−Pacific Conference on Electron Microscopy
2004. 6. 7−11, Kanazawa


Tetsuro Takamatsu, Hideo Tanaka
In situ imaging of calcium dynamics in the Langendorff−perfused heart
The 7th Japan−China Joint Seminar on Histochemistry and Cytochemistry Symposium "Advances in Imaging Technology and Morphomertry"
2004. 10. 21−23 武漢


Tetsuro Takamatsu
NIR Laser−Induced Microdisruption and Its Biomedical Applications
The 12th International Congress of Histochemistry and Cytochemistry Symposium "Symposium: In situ Visualization and manipulation of functional molecules"
2004. 7. 24−28 San Diego


Oyamada M
Imaging of altered expression and function of gap junctions during carcinogenesis and heart disease
Medical Photonics Symposium,
2004.2.23−24, Hamamatsu,


高松哲郎
光学顕微鏡による生体機能の計測と制御技術
第45回日本組織細胞化学会総会・学術集会
2004.10.29−30. 鹿児島県


高松哲郎
光によるナノサ−ジェリ−
日本顕微鏡学会ニュ−マイクロスコ−プ分科会シンポジウム
「ナノクリスタルのバイオイメ−ジングへの 応用」
2004. 3. 18, 東京


高松哲郎
2光子吸収を用いた生体機能分子の制御
第51回応用物理学関係連合講演会シンポジウム
「生体機能のフォトニクス制御技術」
2004. 3. 28−31. 八王子


高松哲郎
レ−ザ顕微鏡を使いこなすための基本
レ−ザ顕微鏡研究会ワ−クショップレクチャ−講
2004.7.1−2.


高松哲郎
生きた細胞から組織の観察, 基礎
第29回日本組織細胞化学講習会
2004.8.4−6. 甲府


高松哲郎
光による機能分子の制御
日本レ−ザ−医学会総会シンポジウム
「レ−ザ−光を用いたナノ/マイクロイメ−ジング」
2004.11.11−12.


高松哲郎
光によるナノサ−ジェリ−
日本顕微鏡学会ニュ−マイクロスコ−プ分科会シンポジウム
「ナノクリスタルのバイオイメ−ジングへの応用」
2004.3.18, 東京


高松哲郎
2光子吸収を用いた生体機能分子の制御
第51回応用物理学関係連合講演会シンポジウム
「生体機能のフォトニクス制御技術」
2004.3.28−31. 八王子


小山田正人, 平川永徳, 鈴木敏弘, 高松哲郎
細胞間結合装置の局在・機能と病態発生.
第93回日本病理学会総会ワークショップ
2004.6.9−11. 北海道.


小山田正人, 田邉卓爾, 高松哲郎
多光子CALIとEGFPを用いた生細胞内蛋白質機能阻害
第13回日本バイオイメ−ジング学会シンポジウム
2004.11.5−7. 京都


田中秀央, 高松哲郎
カルシウムイメ−ジングで見る心臓の興奮伝導障害
第13回日本バイオイメ−ジング学会公開シンポジウム
2004.11.5−7. 京都


 2003

論文


Ito H, Kamoi K, Yokoyama K, Yamada K, Nishimura T.
Visualization of prostate cancer using dynamic contrast-enhanced MRI: comparison with transrectal power Doppler ultrasound.
Br J Radiol. 2003 Sep;76(909):617-24.


Konishi E, Nakashima Y, Manabe T, Mazaki T, Wada Y.
Irritated seborrheic keratosis of the external ear canal.
Pathol Int. 2003 Sep;53(9):622-626.


Konishi E, Nakashima Y, Smyrk TC, Masuda S.
Clear cell carcinoid tumor of the gallbladder. A case without von Hippel-Lindau disease.
Arch Pathol Lab Med. 2003 Jun;127(6):745-7.


Konishi E, Ibayashi N, Yamamoto S, Scheithauer BW.
Isolated intracranial Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy).
AJNR Am J Neuroradiol. 2003 Mar;24(3):515-8.


Konishi E, Nakashima Y, Iwasaki T.
Immunohistochemical analysis of retroperitoneal Mullerian cyst.
Hum Pathol. 2003 Feb;34(2):194-8.


Tanaka H, Takamatsu T
Spatiotemporal Visualization of Intracellular Ca2+ in Living Heart Muscle Cells Viewed by Confocal Laser Scanning Microscopy.
Acta Histochem.Cytochem 36 (3): 193-204, 2003


Naito AT, Tominaga A, Oyamada M, Oyamada Y, Shiraishi I, Monzen K, Komuro I, Takamatsu T
Early stage-specific inhibitions of cardiomyocyte differentiation and expression of Csx/Nkx-2.5 and GATA-4 by phosphatidylinositol 3-kinase inhibitor LY294002.
Exp Cell Res. 2003 Nov 15;291(1):56-69.


Tsujii E, Tanaka H, Oyamada M, Fujita K, Hamamoto T, and Takamatsu T
In situ visualization of the intracellular Ca2+ dynamics at the border of the acute myocardial infarct.
Mol Cell Biochem. 2003 Jun;248(1-2):135-9.


Suzuki T, Takamatsu T, Oyamada M
Expression of gap junction protein connexin43 in the adult rat cochlea: Comparison with connexin26.
J Histochem Cytochem 51:903-912, 2003


Hirakawa H, Okajima S, Nagaoka T, Takamatsu T, Oyamada M
Loss and recovery of the blood-nerve barrier in the rat sciatic nerve after crush injury are associated with expression of intercellular junctional proteins.
Exp Cell Res 284:194-208, 2003


著書


田邉卓爾, 高松哲郎
マルチフォトンレ−ザ−顕微鏡. 光による計測と制御.
田邦昭編. 初めてでもできる共焦点顕微鏡活用プロトコ−ル
実験医学別冊. 東京: 羊土社, 187−191, 2003


万井弘基, 田中秀央, 高松哲郎
ニポウ板を使った共焦点顕微鏡.
高田邦昭編. 初めてでもできる共焦点顕微鏡活用プロトコ−ル.
実験医学別冊. 東京: 羊土社, 169−200, 2003


学会発表


Tanaka H
Real−time confocal visualization of intracellular calcium dynamics in the whole heart
CVRTI seminar: 2004
2004 November 7: University of Utah, Salt Lake City, USA.


Tanaka H, Tsujii E, Oyamada M, Takamatsu T
Arrhythmogenic potentials of intracellular Ca2+ waves viewed by in situ real−time confocal microscopy
Keystone Symposia, Molecular Pathology of Cardiac Arrhythmias.
2003 January14−19: Santa Fe, New Mexico, U. S. A.


Hirakawa H, Okajima S, Nagaoka T, Kubo T, Oyamada M, Takamatsu T
Changes of blood−nerve barrier and connexin expression of rat sciatic nerves after crush injury
2003 International Gap Junction Conference.
2003 August 23−28: Cambridge, UK


Oyamada M, Tsujii E, Tanaka H, Takamatsu T
Inhomogeneous gap−junctional communication at the border zone of acute myocardial infarcts suggested by heterogeneities in abnormal Ca2+ dynamics
2003 International Gap Junction Conference.
2003 August 23−28: Cambridge, UK


Oyamada Y, Oyamada M, Takamatsu T
Connexin expression at the early stages of in vitro cardiomyocyte differentiation of pluripotent embryonic cells
2003 International Gap Junction Conference.
2003 August 23−28: Cambridge, UK


Suzuki T, Matsunami T, Hisa Y, Takamatsu T, Oyamada M
Expression of gap junction proteins connexin43 and connexin26 in the adult rat cochlea
2003 International Gap Junction Conference.
2003 August 23−28: Cambridge, UK


Hamamoto T, Tanaka H, Tsujii E, Mani H, Tanabe T, Oyamada M, Takamatsu T
Simultaneous visualization of intracellular Ca2+ dynamics in purkinje fibers and ventricular myocytes by in situ real−time confocal microscopy
Scientific Sessions 2003. American Heart Association.
2003 November 9−12: Orland, Florida, USA


Tanaka H, Tsujii E, Mani H, Hamamoto T, Tanabe T, Oyamada M, Takamatsu T
Novel Stimulation−induced Ca2+ waves contribute to spatiotemporal Ca2+ alternans in langendorff−perfused rat heart under ischemia/reperfusion injury
Scientific Sessions 2003. American Heart Association.
2003 November 9−12: Orland, Florida, USA


Yamamoto Y, Shiraishi I, Hamaoka K, Takamatsu T
Embryonic pulmonary vascular development is resgulated by balanced expression of VEGF receptors, Flk−1 and Flt−1
43rd Annual Meeting of American Society of Cell Biology.
2003 December 17: San Francisco, U. S. A


Tanabe T, Dai P, Nakagami T, Tanaka H, Oyamada M, Takamatsu T
Selective Attenuation of Connexin43 Gap Junctional Communication by Chromophore−Assisted Laser Inactivation with Two−Photon Absorption
43rd Annual Meeting of American Society of Cell Biology.
2003 December 17: San Francisco, U. S. A


高松哲郎
光による細胞機能の制御
日本レ−ザ−医学会シンポジウム
「レ−ザ顕微鏡の最近の進歩」オ−ガナイザと講演.
2003.11.15. 岐阜


高松哲郎
共焦点レ−ザ顕微鏡の基礎と現状
LSMセミナ−.
2003.1.25. 東京


田中秀央, 高松哲郎
in situで見る心臓の細胞内カルシウムシグナルの動態
レ−ザ−顕微鏡研究会第29回講演会
2003.7.2. 和光


高松哲郎
細胞機能のin situ可視化
日本顕微鏡学会第59回学術講演会,シンポジウム
「ニュ−マイクロスコ−プで捉えた各種病態解析」
2003.6.7.-9. 札幌


小山田正人
キャップ結合とヒト疾患
日本顕微鏡学会第59回学術講演会臨床電子顕微鏡学会合同シンポジウム
「組織のホメオスタシスを守る細胞装置ギャップ結合と
タイト結合の構造,機能.病態」
2003.6.7-9. 札幌


高松哲郎
レ−ザ顕微鏡を使いこなすための基本
レ−ザ−顕微鏡研究会第29回講演会
2003.7.1−2. 和光


高松哲郎, 田邉卓爾
光による細胞・組織の機能制御
第44回日本組織細胞化学会学術集会
2003.10.30.  東京


Tanabe T, Tanaka H, Tsujii E, Hamamoto T, Nakajo T, Oyamada M, Takamatsu T
Fabrication of Aligned Cardiomyocytes Using Two−Photon Absorptioa
76th Annual Scientific Meeting, Japanese Circulation Society.
2003 March 28−30: Fukuoka


Tanaka H, Tsujii E, Hamamoto T, Nakajo T, Tanabe T, Oyamada M, Takamatsu T
Spatiotemporal diversity of intracellular calcium waves at the epicardial border zone of the acute myocardial infarct of the rat
Featured Reseach Session, 76th Annual Scientific Meeting, Japanese Circulation Society.
2003 March 28−30: Fukuoka


Tanaka H, Tsujii E, Mani H, Hamamoto T, Tanabe T, Oyamada M, Takamatsu T
Sequential alterations of the intracellular calcium dynamics in the ischemic rat heart
International Society of heart Research, the 20th Annual Meeting of the Japanese Section.
2003 November 23: Tokyo, Japan


 2002

論文


Tanaka H, Oyamada M, Tsujii E, Nakajo T, Takamatsu T
Excitation-Dependent Intracellular Ca2+ Waves at the Border Zone of the Cryo-injured Rat Heart Revealed by Real-time Confocal Microscopy
J Mol Cell Cardiol vol. 34 1501-1512 2002 Fujita K, Takamatsu T
Real-time in situ calcium imaging with single and two-photon confocal microscopy.
In: Confocal and Two-photon Microscopy, Diaspro A (ed.) John Wiley & Sons 483-498, 2002


Oyamada M, Oyamada Y, Kaneko T, Takamatsu T
Regulation of gap junction protein (connexin) genes and function in differentiating ES cells.
In: Methods Mol Biol: Embryonic Stem Cells: Methods and Protocols 185: 63-69 2002


Oyamada Y, Zhou W, Oyamada H, Takamatsu T, Oyamada M
Dominant-negative connexin43-EGFP inhibits calcium-transient synchronization of primary neonatal rat cardiomyocytes.
Exp Cell Res 273 (1): 85-94 2002


 2001

論文


Oyamada M, Tsujii E, Tanaka H, Matsushita T, Takamatsu T
Abnormalities in gap junctions and calcium dynamics in cardiomyocytes at the border zone of myocardial infarcts.
Cell Communication Adhesion 8: 335-338, 2001


Tanaka H, Takamatsu T
Calcium spots -Elementary signals in response to mechanical stress in vascular endothelial cells-.
Circ. Res. 88: 852-854, 2001


Kaneko T, Fujita K, Tanaka H, Oyamada M, Nakamura O, Kawata S, Takamatsu T
The real-time two-photon microscopy and its application for in situ imaging.
Acta Histochem.Cytochem 34 (6): 399-403, 2001


Suzuki T, Oyamada M, Takamatsu T
Different regulation of connexin26 and ZO-1 in cochleas of developing rats and of guinea pigs with endolymphatic hydrops.
J Histochem Cytochem 49 (5): 573-586, 2001


Nakanouchi T, Okihara K, Kojima M, Ukimura O, Yokoyama K, Takamatsu T, Miki T
Possible use of transrectal power doppler imaging as an indicator of microvascular density of prostate cancer
Urology 58: 573-577, 2001


Okada K, Yokoyama K, Okihara K, Ukimura O, Kojima M, Miki T, TakamatsuT
Immunohistochemical localization of platelet-derived endothelial cellgrowth factor expression and its relation to angiogenesis in prostate.
Urology 57: 376-381, 2001


著書


Oyamada M, Oyamada Y, Kaneko T, Takamatsu T
Regulation of gap junction protein (Connexin) genes and function in differentiating ES cells
Molecular Biology Vol. 185: Embryonic stem cells
Methods and protocols, Turksen K Ed, 63−70, Humana Press Inc, Totowa, NJ, 2001. 11


Fujita K, Takamatsu T
Real−time in situ calcium imaging with single and two−photon confocal microscopy
Confocal and Two−photon Microscopy:
Foundations Applications and Advances, Diaspro A, Ed, pp483−498, John Wiley & Sons, NY, 2001


 2000

論文


Fujita K, Nakamura O, Kaneko T, Oyamada M, Takamatsu T, Kawata S
Confocal multipoint multiphoton excitation microscope with microlens and pinhole arrays.
Opt Comm 174: 7-12, 2000 Hama T, Oyamada M, Dejima K, Takanaka H, Takamatsu T
Expression of gap junctional protein connexins in human nasal epithelium, and its contribution to intercellular calcium signalling.
Acta Histochem Cytochem 33 (1): 23-30, 2000


Kaneko T, Tanaka H, Oyamada M, Kawata S, Takamatsu T
Three distinct types of Ca(2+) waves in Langendorff-perfused rat heart revealed by real-time confocal microscopy.
Circ Res 86 (10): 1093-1099, 2000


Okada K, Kojima M, Naya Y, Kamoi K, Yokoyama K, Takamatsu T, Miki T
Correlation of histological inflammation in needle biopsy specimens with serum prostate- specific antigen levels in men with negative biopsy for prostate cancer.
Urology 55 (6): 892-898, 2000


Oyamada M, Oyamada Y, Komatsu K, Mori M, Takamatsu T
In vitro cardiomyocytic differentiation of mouse embryonic stem cells deficient in gap junction protein connexin43.
Cardiac and Vascular Regeneration 1 (1): 54-64, 2000


Ogawa H, Oyamada M, Mori T, Mori M, Shimizu H
Relationship of gap junction formation to phosphorylation of connexin43 in mouse preimplantation embryos.
Mol Reprod Dev 55 (4): 393-398, 2000


 1999

論文


Matsushita T, Oyamada M, Fujimoto K, Yasuda Y, Masuda S, Wada Y, Oka T, Takamatsu T
Remodeling of cell-cell and cell-extracellular matrix interactions at the border zone of rat myocardial infarcts.
Circ Res 85 (11): 1046-1055, 1999


Fujita S, Nakamura O, Kaneko T, Oyamada M, Takamatsu T, Kawata S
Real-time imaging of two-photon-induced fluorescence microscope using a rotating microlens array.
ProcSPIE 3740: 390-393, 1999


Ibata Y, Okamura H, Tanaka M, Tamada Y, Hayashi S, Iijima N, Matsuda T, Munekawa K, Takamatsu T, Hisa Y, Shigeyoshi Y, Amaya F
Functional morphology of the suprachiasmatic nucleus.
Front Neuroendocrinol 20 (3): 241-268, 1999


Kubo T, Sawada K, Hirakawa K, Shimizu C, Takamatsu T, Hirasawa Y
Histiocyte reaction in rabbit femurs to UHMWPE, metal, and ceramic particles in different sizes.
J Biomed Mater Res 45 (4): 363-369, 1999


Fujita K, Nakamura O, Kaneko T, Kawata S, Oyamada M, Takamatsu T
Real-time imaging of two-photon-induced fluorescence with a microlens-array scanner and a regenerative amplifier.
J Microsc 194 (Pt 2-3): 528-531, 1999


Matsushita T, Oyamada M, Kurata H, Masuda S, Takahashi A, Emmoto T, Shiraishi I, Wada Y, Oka T, Takamatsu T
Formation of cell junctions between grafted and host cardiomyocytes at the border zone of rat myocardial infarction.
Circulation 100 (19 Suppl): II262-II268, 1999


Nagaoka T, Oyamada M, Okajima S, Takamatsu T
Differential expression of gap junction proteins connexin26, 32, and 43 in normal and crush-injured rat sciatic nerves.
Close relationship between connexin43 and occludin in the perineurium.

J Histochem Cytochem 47 (7): 937-948, 1999


 1998

論文


Gotoh T, Sugihara H, Matsumura T, Katsura K, Takamatsu T, Sawada T
Human neuroblastoma demonstrating clonal evolution in vivo.
Genes Chromosom Cancer 22 (1): 42-49, 1998


Hama T, Takahashi A, Ichihara A, Takamatsu T
Real time in situ confocal imaging of calcium wave in the perfused whole heart of the rat.
Cell Signal 10 (5): 331-337, 1998


Masuda A, Oyamada M, Nagaoka T, Tateishi N, Takamatsu T
Regulation of cytosol-nucleus pH gradients by K+/H+ exchange mechanism in the nuclear envelope of neonatal rat astrocytes.
Brain Res 807 (1-2): 70-77, 1998


Oyamada M, Oyamada Y, Takamatsu T
Gap junctions in health and disease.
Med Electron Microsc 31 (3): 115-120, 1998


Takamatsu T
Confocal microscopy. Applications in research and practice
of pathology.

Anal Quant Cytol Histol 20 (6): 529-532, 1998


Yao XH, Sugihara H, Hattori T, Katsura K, Takamatsu T
Regulation of apoptotic cell death in the pyloric glands of the canine stomach.
Virchows Arch 433 (3): 275-280, 1998


Yasui H, Yoshimura N, Kobayashi Y, Ochiai S, Matsuda T, Takamatsu T, Oka T
Microstructural changes of bile canaliculi in canine liver:
the effect of cold ischemia-reperfusion in orthotopic liver transplantation.

Transplant Proc 30 (7): 3754-3757, 1998


Shiraishi I, Borg TK, Takamatsu T, Onouchi Z
Cell-cell and cell matrix adhesions during formation and arrangement of developing cardiac myofibrils.
The 5th International Symposium on Etiology and Morphogenesis of Congenital Heart Diease, Tokyo 1998


Takamatsu T, Matsusita T, Masuda S, Yokoyama K, Oyamada M
Aberrant expression of cell junctions in ischemic
rat cardiomyocytes.

American Society for Cell Biology 38th Annual Meeting, San Francisco 1998


 1997

論文


Matsushita T, Takamatsu T
Ischaemia-induced temporal expression of connexin43
in rat heart.

Virchows Arch 431 (6): 453-458, 1997


Nagaoka T, Masuda A, Takamatsu T
Lowering extracellular pH raises intracellular calcium in cultured rat astrocytes.
Acta Histochem Cytochem 30 (2): 221-223, 1997


Shiraishi I, Takamatsu T, Price RL, Fujita S
Temporal and spatial patterns of phosphotyrosine immunolocalization during cardiac myofibrillogenesis
of the chicken embryo.

Anat Embryol (Berl) 196 (1): 81-89, 1997


Takahashi ATakamatsu T
Effects of basal [Ca2+]i on calcium handling in Ca(2+)-overloaded rat cultured heart muscle cells.
Cell Signal 9 (8): 617-625, 1997


Tanaka M, Hayashi S, Tamada Y, Ikeda T, Hisa Y, Takamatsu T, Ibata Y
Direct retinal projections to GRP neurons in the suprachiasmatic nucleus of the rat.
Neuroreport 8 (9-10): 2187-2191, 1997


Yokoyama K, Takamatsu T
[Observation of intracellular calcium kinetics with confocal laser scanning microscope].
Tanpakushitsu Kakusan Koso 42 (7 Suppl):1221-1226 1997


Saito T, Oyamada M, Yamasaki H, Mori M, Kudo R
Co-ordinated expression of connexins 26 and 32 in human endometrial glandular epithelium during the reproductive cycle and the influence of hormone replacement therapy.
Int J Cancer 73 (4): 479-485, 1997


Saitoh M, Oyamada M, Oyamada Y, Kaku T, Mori M
Changes in the expression of gap junction proteins (connexins) in hamster tongue epithelium during wound healing and carcinogenesis.
Carcinogenesis 18 (7): 1319-1328, 1997